Insect growth regulator, Thiadizine

1) Common name: buprofezin
2) Structural formula:

3) Chemical name: 2-tert-butylimino-3-isopropyl-5-phenyl-l,3,5-thiadiazinan-4-one
4) Molecular formula: C16HH23N3OS
5) Molecular weight: 305.4
6) CAS no.: 69327-76-0

Physical and chemical properties:
1) Appearance: white crystals (tech., white or pale yellow crystalline powder)
2) Melting point: 104.5 - 105.51oC
3) Vapor pressure: 1.25mPa (25oC)
4) S.g./density: 1.18 (20oC)
5) Solubility:
a) In water: 0.9mg/L (20oC)
b) In chloroform: 520, benzene 370, toluene 320, acetone 240, ethanol 80, hexane
20 (all in g/L, 25oC)
6) Stability: stable in acidic and alkaline media, stable to heat and light.

Technical specifications:
1) Appearance: white or slightly yellow crystals
2) a.i. content (w/w): 95% (minimum)
3) Drying loss(w/w): 0.5% (maximum)
4) Acidity (calculated as H2SO4): (maximum)

Formulation: 40SC, 25EC, 25WP

Analysis: GC (TC, HG 2463. 1-93)

Packaging: 25kg/plastic woven bag or cardboard drum lined with plastic bag

1) Biochemistry: probable chitin synthesis and prostaglandin inhibitor. Hormone disturbing
effect, leading to suppression of ecdysis.
2) Action: persistent insecticide and acaricide with contact and stomach action;
not translocated in the plant. Inhibits molting of nymphs and larvae, leading to
death. Also suppresses oviposition by adults; treated insects lay sterile eggs.
3) Uses:
a) Insecticide with persistent larvicidal action against Homoptera, some Coleoptera
and also Acarina
b) Effective against Cicadellidae and Delphacidae (leafhoppers) in rice; Cicadellidae
in potatoes; Aleyrodidae (whitefly) in citrus, cotton and vegetables; Coccidae,
Diaspididae (scale insects) and Pseudococcidae (mealy bugs) in citrus.

1) Oral: acute oral LD50 for male rats 2198, female rats 2355, male and
female mice >1000mg/kg
2) Skin and eyes: acute percutaneous LD50 for rats >5000mg/kg. Mild skin
irritant (guinea pigs), not irritating to skin and eyes (rabbits)
3) Inhalation: LC50 (4h) for rats >4.57mg/L air
4) NOEL: for male rats 0.90, female rats 1.12mg/kg daily
5) ADI: 0.01mg/kg b.w.
6) Fish: LC50 (48h) for carp 2.7, rainbow trout >1.4mg/L
7) Bees: no direct effect on bees at 2000mg/L (WP formulation)
8) Other: no effect on various predators, non-carcinogenic, non-mutagenic

Payment Term: L/C at sight
Price Term: FOB Shanghai

Sales Terms & Specifications:

Place Of OriginChina
Brand NameAnpon
Price TermsFOB / CIF / EXW(Factory Price)
Terms Of PaymentT/T, Western Union, PayPal, L/C at sight
Supply Ability1,000MT/year
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