L-5-Hydroxy-tryptophan (Griffonia seed extract)

Specification: 98%HPLC

Product Origins: Linnea L-5-Hydroxytryptophan (5-HTP) is a natural extract from the
seeds of the Griffonia simplicifolia tree found principally in the West African
countries of Ghana, Ivory Coast and Togo. Traditional African uses for the plant
include the use of the stem and roots as chewing sticks, leaves to aid in the
healing of wounds, whilst the leaf juice is used as an enema and for the treatment
of kidney ailments. A decoction of the steams and leaves is also used to stop
vomiting, to treat congestion of the pelvis and as an aphrodisiac. The bark-pulp
is applied as a plaster to soft chancres.

From the 1960's chemical investigations on Griffonia simplicifolia seed resulted
in the detection and isolation of several indole derivatives including 5 hydroxy-L-tryptophan,
indole-3-acetylaspartic acid and 5-hyrdroxy indole-3-acetic acid
(5-HIAA). Research also showed 5-HTP to possess antidepressant activity. 5-HTP was
found to be more effective than the tricyclic synthetic drugs which were considered
the standard of care at that time. As a consequence during the 1980's a number
of medicinal specialities containing 5-HTP as the active ingredient were registered
and launched on the market.

Pharmacological Activities: L-5-Hydroxytryptophan is decarboxylated "in vivo" to
yield serotin, a neurohormonal transmitter released by neurones in the brain, spinal
cord and sympathetic ganglia.

Therapeutic Applications: L-5-Hydroxytryptophan is reported to be of greatest benefit
in psychiatric and neurological disorders where there is a deficiency of neural
serotonin. L-5-Hydroxytryptophan is also indicated for its uses in alleviating
the symptoms of a number of common syndromes such as anxiety and depression.
L-5-Hydroxytryptophan is also cited as a natural relaxant, to help alleviate insomnia
by inducing normal sleep, for the treatment of migraine and headaches and
to aid in the control of cravings such as in eating disorders. L-5-Hydroxytryptophan
is also thought to assist and strengthen the immune system and may help to
reduce the risk of artery and heart spasms. L-5-Hydroxytryptophan has also been
cited in the management of Parkinson's disease (PD) and epilepsy.

Therapeutical Categories: Antidepressant, Antiepileptic

Packing: 25kg/drum

Sales Terms & Specifications:

Model No.98%
Place Of OriginGhana
Price TermsFOB / CIF / EXW(Factory Price)
Terms Of PaymentT/T in advance
Minimum Order50 Kilogram
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